Yazar "D-4793-2014" için listeleme
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The Analysis of Lncrna HOTAIR Rs12826786 C > T Polymorphism and Gastric Cancer Susceptibility in A Turkish Population: Lack of Any Association in A Hospital-Based Case-Control Study
Ulger, Y.; Dadas, E.; Kaya, B. Yalinbas; Sumbul, A. T.; Genc, A.; Bayram, S. (2017)The HOX transcript antisense intergenic RNA (HOTAIR), a well-known long noncoding RNA (lncRNA), has been widely identified to participate in pathogenesis of multiple cancers. An aberrant up-regulation and biological functions ... -
Atezolizumab in Patients with Metastatic Urothelial Carcinoma Who Have Progressed After First-line Chemotherapy: Results of Real-life Experiences
Sumbul, Ahmet Taner (2021)Background: Atezolizumab (ATZ) has demonstrated antitumor activity and manageable safety in previous studies in patients with locally advanced or metastatic platinum resistant urothelial carcinoma. Objective: To compare ... -
Clinicohistopathological features and treatment outcomes of neuroendocrine tumors: a single center experience
Kose, Fatih; Sedef, Ali Murat; Sumbul, Ahmet Taner; Mertsoylu, Huseyin; Besen, Ali Ayberk; Sezer, Ahmet; Ozyilkan, Ozgur; Abali, Huseyin (2018)Purpose: Tumor and patient characteristics of neuroendocrine tumors (NET) significantly change between geographical locations that probably induced by environmental and genetic factors throughout the world. Therefore, ... -
Clinicohistopathological Features and Treatment Outcomes of Neuroendocrine Tumors; A Single Center Experience
Sumbul, A. T.; Sedef, A. M.; Kose, F.; Mertsoylu, H.; Sezer, A.; Ozyilkan, O.; Abali, H. (2017) -
Does Cyclin E and P57(Kip2) Expression Have Prognostic and Survival Value in Colorectal Adenocarcinoma?
Ozgur, Tumay; Sumbul, Ahmet Taner; Yaldiz, Mehmet; Temiz, Muhittin; Akdag, Abdurrahman (2018)Introduction: Colorectal cancer is still one of the main causes of cancer death in the world. There is a continous need for novel biomarkers for diagnose, treatment modalities and follow-up. Cyclin E and p57(KIP2) as the ... -
Effect of Adjuvant Extended Temozolamide Treatment in Survival of Patients with Glioblastoma Multiforme
Yildirim, Berna Akkus; Sumbul, Ahmet Taner; Topkan, Erkan; Ozdemir, Yurday; Besen, Ali Ayberk; Guler, Ozan Cem; Sedef, Ali Murat; Onal, Cem (2018)Purpose: The aim of this retrospective cohort study was to evaluate the prognostic effect extended temozolamide on survival outcomes of glioblastoma multiforme patients who were underwent surgery/biopsy followed treated ... -
Flare Phenomenon in Advanced Colorectal Cancer: Cessation of evacizumab after Predefined Cycles of Therapy may not Affect Outcome
Besen, A.Ali; Kose, Fatih; Sumbul, Ahmet T:; Ozdemir, Nuriye; Ozyilkan, Ozgur; Zengin, Nurullah; Abali, Huseyin (2017)Limited number of experimental and clinical studies showed rapid tumor regrowth after bevacizumab cessation in advanced colorectal cancer. We retrospectively evaluated rapid regrowth phenomenon in 105 patients those who ... -
A Functional HOTAIR Rs12826786 C > T Polymorphism Is Associated with Breast Cancer Susceptibility and Poor Clinicopathological Characteristics in A Turkish Population: A Hospital-Based Case-Control Study
Bayram, Suleyman; Sumbul, Ahmet Taner (2016)Hox transcript antisense intergenic RNA (HOTAIR), a long non-coding RNA (lncRNA), is pervasively overexpressed and correlated with tumor invasion, progression, metastasis, and poor prognosis in various human cancers including ... -
The hematologic parameters in metastatic castration-resistant prostate cancer patients treated with abiraterone acetate
Onal, Cem; Sedef, Ali Murat; Kose, Fatih; Oymak, Ezgi; Guler, Ozan Cem; Sumbul, Ahmet Taner; Aksoy, Sercan; Yildirim, Berna Akkus; Besen, Ali Ayberk; Muallaoglu, Sadik; Mertsoylu, Huseyin; Ozyigit, Gokhan (2019)Currently, there are no predictive markers of response to abiraterone. We calculated neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) at baseline and at 4 and 12 weeks after initiation of ... -
The hematologic parameters in metastatic castration-resistant prostate cancer patients treated with abiraterone acetate.
Cem, Onal; Sedef, Ali Murat; Kose, Fatih; Oymak, Ezgi; Guler, Ozan Cem; Sumbul, Ahmet Taner; Aksoy, Sercan; Yildirim, Berna Akkus; Besen, Ali Ayberk; Mullaoglu, Sadik; Mertsoylu, Huseyin; Ozyigit, Gokhan (2019) -
High Pretreatment Neutrophil-Lymphocyte Ratio: A Poor Prognostic Factor for Stage III Non-Small Cell Lung Cancer Patients
Sumbul, Ahmet T.; Batmaci, Celal; Ucar, Edip; Kose, Fatih; Sedef, Ali M.; Yildirim, Berna; Mertsoylu, Huseyin; Sezer, Ahmet; Ozyilkan, Ozgur (2015) -
Influence of Creatinine Clearance on Survival Parameters in Small Cell Lung Cancer Treated with Cisplatin-Based Chemotherapy Regimen
Gozel, Sedat; Sumbul, Ahmet; Sedef, Ali Murat; Besen, Ayberk; Mertsoylu, Huseyin; Batmaci, Celal; Kose, Fatih (2017) -
MicroRNA 211 Expression Is Upregulated and Associated with Poor Prognosis in Colorectal Cancer: A Case-Control Study
Sumbul, Ahmet Taner; Gogebakan, Bulent; Bayram, Suleyman; Batmaci, Celal Yucel; Oztuzcu, Serdar (2015)Increasingly more evidence support the role of the microRNAs (miRNA) in tumorigenesis. The role of up/downregulation microRNA-211 (miR-211) during human tumorigenesis is still contentious and may exhibit tissue-specific ... -
The outcome of loco-regional radiotherapy in metastatic castration-resistant prostate cancer patients treated with abiraterone acetate.
Yildirim, Berna; Cem, Onal; Kose, Fatih; Oymak, Ezgi; Sedef, Ali Murat; Besen, Ali Ayberk; Aksoy, Sercan; Guler, Ozan Cem; Sumbul, Ahmet Taner; Mertsoylu, Huseyin; Ozyigit, Gokhan (2019) -
Patients with Distal Intestinal Gastric Cancer Have Superior Outcome with Addition of Taxanes to Combination Chemotherapy, While Proximal Intestinal and Diffuse Gastric Cancers do not: Does Biology and Location Predict Chemotherapy Benefit?
Sedef, Ali Murat; Kose, Fatih; Sumbul, Ahmet Taner; Dogan, Ozlem; Besen, Ali Ayberk; Tatli, Ali Murat; Mertsoylu, Huseyin; Sezer, Ahmet; Muallaoglu, Sadik; Ozyilkan, Ozgur; Abali, Huseyin (2015)Gastric cancer, with one million new cases observed annually, and its dismal prognosis, is one of the leading causes of cancer-related mortalities. Systemic chemotherapy is the main treatment modality in advanced gastric ... -
Pertuzumab, Trastuzumab and Taxane Combination for Visceral Organ Metastatic Patients: Real Life Practice Results
Esin, E.; Oksuzoglu, O. B. Cakmak; Bilici, A.; Cicin, I.; Aksoy, S.; Alacacioglu, A.; Kaplan, M. A.; Cabuk, D.; Sumbul, A. T.; Paydas, S.; Sakin, A.; Er, O.; Korkmaz, T.; Yildirim, N.; Artac, M.; Harputluoglu, H.; Yumuk, P. F.; Basaran, G.; Uluc, B. Oyan; Demirci, U. (2018) -
Pertuzumab, trastuzumab and taxane-based treatment for visceral organ metastatic, trastuzumab-naive breast cancer: real-life practice outcomes
Sumbul, A. T. (2019)PurposeIn this study, we aimed to describe the real-life practice outcomes of pertuzumab-trastuzumab-taxane (PTT) combination in visceral organ metastatic, trastuzumab-naive breast cancer (BC) patients.MethodsThis study ... -
Polymorphisms in Human Telomerase Reverse Transcriptase (Htert) Gene and Susceptibility to Gastric Cancer in A Turkish Population: Hospital-Based Case-Control Study
Bayram, Suleyman; Ulger, Yakup; Sumbul, Ahmet Taner; Kaya, Berrin Yalinbas; Genc, Ahmet; Rencuzogullari, Eyyup; Dadas, Erdogan (2016)Erosion of telomeres, tandem nucleotide repeats (TTAGGG) that cap the end of eukaryotic chromosomes, has been related with carcinogenesis. The human telomerase reverse transcriptase (hTERT) gene is encoded the rate-limiting ... -
Prognostic Role of fox-p3 Positive T-Regulatory Cells in Curatively Resected NSCLC Other than Stage IA
Kose, Fatih; Besen, Ayberk; Findikcioglu, Alper; Canbolat, Tuba; Ozdemir, Yurday; Sedef, Ali M.; Mertsoylu, Huseyin; Sumbul, Ahmet T.; Ozyilkan, Ozgur; Abali, Huseyin (2015) -
Prognostic Role of Pretreatment Level Hemoglobin Levels in Patients with Local Advanced Rectum Cancer Treated with Preoperative Chemotherapy
Yildirim, Berna Akkus; Sumbul, Ahmet Taner; Guler, Ozan Cem; Sedef, Ali Murat; Onal, Cem; Topkan, Erkan (2018)Purpose: This study aims to systematically evaluate the relationship between baseline blood count levels, simply and basically initiated, and treatment response in locally advanced rectal cancer patients treated with ...