Show simple item record

dc.contributor.authorTohma, Yusuf Aytac
dc.contributor.authorGunabakan, Emre
dc.contributor.authorHaberal, Asuman Nihan
dc.contributor.authorAyhan, Ali
dc.date.accessioned2019-05-06T08:45:55Z
dc.date.available2019-05-06T08:45:55Z
dc.date.issued2018
dc.identifier.issn1643-8876
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6107091/
dc.identifier.urihttp://hdl.handle.net/11727/3189
dc.description.abstractSynchronous ovarian tumours are rare. Management of these patients can differ from that of patients with uniform tumours. We present a case of synchronous epithelial ovarian cancer and malignant mixed Mullerian tumour in different ovaries, its follow-up and management until death. To our knowledge this is the second case in the English literature to date. A 61-year-old woman with bilateral adnexal masses underwent complete debulking surgery for ovarian cancer. The final pathology was reported as malignant mixed Mullerian tumour in the right ovary with intact borders and stage 2 grade 3 serous carcinoma in the left ovary. She had a 17-month disease-free interval after 6 cycles of paclitaxel and carboplatin. Recurrence of malignant mixed Mullerian tumour was reported in the pathology after secondary debulking including a partial ileal resection. After 6 cycles of gemcitabine and cisplatin she had a widespread recurrence in the thorax and abdomen. The patient died of disease recurrence at the 25th month after diagnosis. Coexistence of serous and malignant mixed Mullerian tumour in different ovaries is very rare. The main treatment is complete cytoreduction followed with chemotherapy. Platinum-taxane based chemotherapy resulted in an acceptable disease-free interval in our case, but it is not standard yet. A management protocol may be developed with the increasing number of similar cases in the literature.en_US
dc.language.isoengen_US
dc.relation.isversionof10.5114/pm.2018.77312en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSynchronous ovarian tumoursen_US
dc.subjectSerous adenocarcinomaen_US
dc.subjectMalignant mixed Mullerian tumouren_US
dc.titleBilateral synchronous ovarian tumours: an uncommon case and review of the literatureen_US
dc.typereviewen_US
dc.relation.journalMENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNYen_US
dc.identifier.volume17en_US
dc.identifier.issue2en_US
dc.identifier.startpage97en_US
dc.identifier.endpage100en_US
dc.identifier.wos000439885000009


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record