dc.contributor.author | Tutuncu, Neslihan Basci | |
dc.contributor.author | Emral, Rifat | |
dc.contributor.author | Tetiker, Tamer | |
dc.contributor.author | Sahin, Ibrahim | |
dc.contributor.author | Sari, Ramazan | |
dc.contributor.author | Kaya, Ahmet | |
dc.contributor.author | Yetkin, Ilhan | |
dc.contributor.author | Cil, Sefika Uslu | |
dc.date.accessioned | 2019-05-25T14:50:00Z | |
dc.date.available | 2019-05-25T14:50:00Z | |
dc.date.issued | 2018 | |
dc.identifier.issn | 1472-6823 | |
dc.identifier.uri | https://bmcendocrdisord.biomedcentral.com/track/pdf/10.1186/s12902-018-0238-2 | |
dc.identifier.uri | http://hdl.handle.net/11727/3307 | |
dc.description.abstract | Background: Limited real-world data are currently available on hypoglycemia in diabetes patients. The International Operations Hypoglycemia Assessment Tool (IO HAT) study was designed to estimate hypoglycemia in insulin-treated type I (T1DM) and type II (T2DM) diabetes mellitus patients from 9 countries. The data from Turkey cohort are presented here.
Methods: A non-interventional study to determine the hypoglycemia incidence, retrospectively and prospectively, in Turkish T1DM and T2DM patients using a 2-part self-assessment questionnaire.
Results: Overall, 2348 patients were enrolled in the Turkey cohort (T1DM = 306 patients, T2DM = 2042 patients). In T1DM patients, 96.8% patients reported hypoglycemic events (Incidence rate [IR]: 68.6 events per patient-year [ppy]), prospectively, while 74.0% patients reported hypoglycemic events (IR: 51.7 events ppy), retrospectively. In T2DM patients, 95.9% patients (IR: 28.3 events ppy) reported hypoglycemic events, prospectively, while 53.6% patients (IR: 23.0 events ppy) reported hypoglycemic events, retrospectively. Nearly all patients reported hypoglycemia during the prospective period.
Conclusions: This is a first patient-reported dataset on hypoglycemia in Turkish, insulin-treated diabetes patients. A high incidence of patient-reported hypoglycemia confirms that hypoglycemia remains under-estimated. Hypoglycemia increased healthcare utilization impacting patients' quality of life. Hypoglycemia remains a common side effect with insulin-treatment and strategies to optimize therapy and reduce hypoglycemia occurrence in diabetes patients are required. | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.1186/s12902-018-0238-2 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Diabetes | en_US |
dc.subject | Turkey | en_US |
dc.subject | Hypoglycemia | en_US |
dc.subject | IO HAT | en_US |
dc.subject | Insulin | en_US |
dc.subject | Non-interventional | en_US |
dc.title | An international survey on hypoglycemia among insulin-treated type I and type II diabetes patients: Turkey cohort of the non-interventional IO HAT study | en_US |
dc.type | article | en_US |
dc.relation.journal | BMC ENDOCRINE DISORDERS | en_US |
dc.identifier.volume | 18 | en_US |
dc.identifier.wos | 000425180000001 | en_US |
dc.identifier.scopus | 2-s2.0-85041858991 | en_US |
dc.contributor.pubmedID | 29433560 | en_US |
dc.contributor.orcID | 0000-0002-1816-3903 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | en_US |
dc.contributor.researcherID | ABG-5027-2020 | en_US |