Basit öğe kaydını göster

dc.contributor.authorYikilmaz, A.S.
dc.contributor.authorMousa, U.
dc.contributor.authorNar, A.
dc.date.accessioned2019-06-28T10:08:02Z
dc.date.available2019-06-28T10:08:02Z
dc.date.issued2018
dc.identifier.issn15849244
dc.identifier.urihttps://umbalk.org/wp-content/uploads/2018/09/11.MALE-SEX-AND-TUMOR-DIAMETER-ARE-INDEPENDENT.pdf
dc.identifier.urihttp://hdl.handle.net/11727/3731
dc.description.abstractBackground. Differentiated thyroid cancer (DTC) is one of the most frequently observed neoplasms today. Recurrence of DTC has been previously reported to be dependent on tumor characteristics, the tumor size, the presence of lymph node metastasis, the presence of extra thyroid invasion, the presence of distant metas‑ tasis, oncogenes such as B‑RAF proto‑oncogene, ad‑ vanced age and male sex. However, many studies have failed to associate many of these data with relapse. The objective of the study was to evaluate the re‑ lationship between some histopathological and mor‑ phological findings with thyroid cancer relapse or per‑ sistent disease in a cohort of 393 DTC patients. Methods. We retrospectively analyzed 393 subjects with DTC, diagnosed in our institution between January 2000 and December 2010. Results. Histopathological analysis indicated papil‑ lary carcinoma in 362 (92.1%) subjects and follicular carcinoma in 31 (7.9%) subjects. Eighty‑two (20.9%) of the subjects relapsed or had persistent disease. Male subjects had a higher trend for relapse (RR 1.739 %95 CI: 1.059‑2.856) p=0.029). 18.8% of female sub‑ jects relapsed or had persistent disease, whereas the relapse rate was 30.4% in male subjects. Every 1 cm increase in tumor size increased the risk of relapse by 25% (RR=1.25, 95% CI: 1.11‑1.41, p<0.001). Male sex, nodule diameter, and tumor diameter were detected to be independent parameters for relapse or persistent disease (p=0.002; p<0.0001, p<0.001 respectively). Conclusion. We demonstrated that tumor diameter and male sex were the only parameters affecting re‑ lapse or persistent disease in our cohort. A possible reason for different reports from different studies may be non‑standardization of study protocols and surgical cure rates. Copyright © 2018 Balkan Medical Union.en_US
dc.language.isoengen_US
dc.relation.isversionof10.31688/ABMU.2018.53.3.11en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDifferentiated thyroid canceren_US
dc.subjectFollicular carcinomaen_US
dc.subjectPapillary carcinomaen_US
dc.subjectRelapseen_US
dc.titleMale sex and tumor diameter are independent risk factors for relapse or persistent disease in differentiated thyroid canceren_US
dc.typearticleen_US
dc.relation.journalArchives of the Balkan Medical Unionen_US
dc.identifier.volume53en_US
dc.identifier.issue3en_US
dc.identifier.startpage381en_US
dc.identifier.endpage386en_US
dc.identifier.scopus2-s2.0-85053345565en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


Bu öğenin dosyaları:

Thumbnail

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster