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dc.contributor.authorYildirim, Tulin
dc.contributor.authorKarakurum Göksel, Basak
dc.contributor.authorDemir, Senay
dc.contributor.authorTokmak, Naime
dc.contributor.authorTan, Meliha
dc.date.accessioned2019-09-13T08:15:52Z
dc.date.available2019-09-13T08:15:52Z
dc.date.issued2016
dc.identifier.issn1300-0144
dc.identifier.urihttp://journals.tubitak.gov.tr/medical/issues/sag-16-46-3/sag-46-3-37-1411-77.pdf
dc.identifier.urihttp://hdl.handle.net/11727/3903
dc.description.abstractBackground/aim: The aim of this study was to evaluate perfusion computed tomography (PCT) findings in patients with Alzheimer disease and to compare them with those of patients without dementia. Materials and methods: PCT was performed in 35 patients: 20 with Alzheimer disease (mean age, 69.7 +/- 5.5 years) and 15 control subjects (mean age, 67.5 +/- 3.5 years). Control subjects were elderly individuals with no cognitive problems who were admitted with headaches. All PCT examinations were performed on a 4-slice CT unit. The PCT analysis software program was used to calculate regional cerebral blood flow (rCBF), regional cerebral blood volume (rCBV), regional time-to-peak (rTTP) values in the bilateral frontal, temporal, and occipital cortices, and bilateral lentiform nucleus. Results: rCBF values in the bilateral frontal and temporal cortices and bilateral lentiform nucleus were significantly lower in the patients with Alzheimer disease than in the control subjects. There were no significant differences in rCBV values between Alzheimer disease and the control group. rTTP values in all cortical areas and bilateral lentiform nucleus were significantly higher in the patients with Alzheimer disease than in the control subjects. Conclusion: PCT is a rapid and reliable imaging modality for evaluating brain perfusion in Alzheimer disease.en_US
dc.language.isoengen_US
dc.relation.isversionof10.3906/sag-1411-77en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAlzheimer diseaseen_US
dc.subjectbrain perfusionen_US
dc.subjectperfusion computed tomographyen_US
dc.titleEvaluation of brain perfusion in Alzheimer disease with perfusion computed tomography and comparison to elderly patient without dementiaen_US
dc.typearticleen_US
dc.relation.journalTURKISH JOURNAL OF MEDICAL SCIENCESen_US
dc.identifier.volume46en_US
dc.identifier.issue3en_US
dc.identifier.startpage834en_US
dc.identifier.endpage839en_US
dc.identifier.wos000374327500037en_US
dc.identifier.scopus2-s2.0-84964038775en_US
dc.contributor.pubmedID27513264en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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