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dc.contributor.authorSezer, Siren
dc.contributor.authorBal, Zeynep
dc.contributor.authorTutal, Emre
dc.contributor.authorUyar, Mehtap Erkmen
dc.contributor.authorAcar, Nurhan Ozdemir
dc.date.accessioned2019-12-16T07:29:50Z
dc.date.available2019-12-16T07:29:50Z
dc.date.issued2014
dc.identifier.issn0148-6071
dc.identifier.urihttp://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4361702&blobtype=pdf
dc.identifier.urihttp://hdl.handle.net/11727/4449
dc.description.abstractBackground: There is no consensus on the type, time of initiation, or duration of use of enteral nutrition in patients with chronic kidney disease (CKD). This study aimed to compare the effects of a renal-specific oral nutrition supplement (RS-ONS) and a standard recommended nutrition regime on biochemical and nutrition markers in malnourished patients with CKD on hemodialysis. Methods: Sixty-two malnourished patients with CKD, divided into experimental (RS-ONS; n = 32; mean [SD] age, 62.0 [11.3] years; 55.2% female) and control (CON; n = 30; mean [SD] age, 57.2 [12.3] years; 31% female) groups, were evaluated for anthropometric, biochemical, and inflammatory parameters. Results: Mean (SD) serum albumin levels were significantly increased in the RS-ONS group from 3.5 (0.3) g/dL at baseline to 3.7 (0.2) g/dL at 6 months (P = .028). Significantly fewer patients had serum albumin levels of <3.5 g/dL after month 6. Dry weight of patients significantly increased in the RS-ONS but decreased in the CON groups (P < .001 for each). Percent change from baseline revealed negative results for bioelectrical impedance analysis (P < .001) in the CON group. Malnutrition inflammation score at 6 months (P = .006) and erythropoietin (EPO) dose requirements were higher in the CON group (P = .012). Conclusions: Our findings indicate that consuming RS-ONS improves serum albumin and anthropometric measures, as well as reduces EPO dose, in patients with CKD.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1177/0148607113517266en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectchronic renal diseaseen_US
dc.subjectmalnutritionen_US
dc.subjectdialysisen_US
dc.subjectoral nutritional supplementsen_US
dc.subjectanthropometricsen_US
dc.titleLong-Term Oral Nutrition Supplementation Improves Outcomes in Malnourished Patients With Chronic Kidney Disease on Hemodialysisen_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF PARENTERAL AND ENTERAL NUTRITIONen_US
dc.identifier.volume38en_US
dc.identifier.issue8en_US
dc.identifier.startpage960en_US
dc.identifier.endpage965en_US
dc.identifier.wos000344314500007en_US
dc.identifier.scopus2-s2.0-84910086679en_US
dc.contributor.pubmedID24436491en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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