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dc.contributor.authorOzkan, Eylem Akar
dc.contributor.authorOzdemir, B. Handan
dc.contributor.authorAkcay, Eda Yilmaz
dc.contributor.authorAtilgan, Alev Ok
dc.contributor.authorHaberal, Mehmet
dc.date.accessioned2024-02-27T11:18:04Z
dc.date.available2024-02-27T11:18:04Z
dc.date.issued2014
dc.identifier.issn1304-0855en_US
dc.identifier.urihttp://hdl.handle.net/11727/11652
dc.description.abstractT-cell posttransplant lymphoproliferative disorders after solid-organ transplant are rare and may be clinically aggressive. A 3-year-old boy had liver transplant from his grandfather because of hepatoblastoma. The immunosuppressive regimen was based on tacrolimus and prednisolone. At 22 months after transplant (age, 5 years)., the patient presented to the hospital because of severe cough. Computed tomography scan of the chest showed a large left mediastinal mass (9 x 7.2 x 7 cm) and left pleural effusion. A Tru-Cut biopsy of the mediastinal mass showed diffuse infiltration with blast cells, and the diagnosis of 1-cell acute lymphoblastic leukemia was made. Immunohistochemical examination of blasts showed strong and diffuse terminal deoxynucleotidyl transferase and CD3 antibody expression; Ki-67 proliferation index was > 95%, and tumor cells were negative for Epstein-Barr virus. Tacrolimus was stopped, sirolimus was started, and chemotherapy was given, but he died 2 months after diagnosis because of chemotherapy-induced sepsis. Monomorphic 1-cell posttransplant lymphoproliferative disorder with features of acute lymphoblastic leukemia and lymphoblastic lymphoma is rare after liver transplant.en_US
dc.language.isoengen_US
dc.relation.isversionof10.6002/ect.25Liver.P29en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatic failureen_US
dc.subjectHepatoblastomaen_US
dc.subjectLymphomaen_US
dc.subjectPosttrans plant lymphoproliferative disorderen_US
dc.titleT-Cell Acute Lymphoblastic Leukemia After Liver Transplanten_US
dc.typearticleen_US
dc.relation.journalEXPERIMENTAL AND CLINICAL TRANSPLANTATIONen_US
dc.identifier.volume12en_US
dc.identifier.startpage139en_US
dc.identifier.endpage141en_US
dc.identifier.wos000335626600031en_US
dc.identifier.scopus2-s2.0-84897420561en_US
dc.contributor.pubmedID24635812en_US
dc.contributor.orcIDhttps://orcid.org/0000-0002-7528-3557en_US
dc.contributor.orcIDhttps://orcid.org/0000-0001-6831-9585en_US
dc.contributor.orcIDhttps://orcid.org/0000-0001-8595-8880en_US
dc.contributor.orcIDhttps://orcid.org/0000-0002-3462-7632en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDX-8540-2019en_US
dc.contributor.researcherIDAAK-1960-2021en_US
dc.contributor.researcherIDAAK-3333-2021en_US
dc.contributor.researcherIDAAJ-8097-2021en_US


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