High Prolactin Level as a Predictor of Vasospasm in Aneurysmal Subarachnoidal Hemorrhage
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Tarih
2017Yazar
Kircelli, Atilla
Coven, Ilker
Duman, Enes
Pinar, Huseyin Ulas
Basaran, Betul
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Background: Aneurysmal subarachnoid hemorrhage (aSAH) is a destructive syndrome with a mortality rate of 50%. Recent studies have also suggested a high pervasiveness of hypothalamic-pituitary insufficiency in up to 45% of patients after aSAH. Prolactin has been associated with the pathogenesis of hypertensive irregularities that are linked to pregnancy.
Material/Methods: We identified a group of 141 patients with spontaneous SAH due to a ruptured cerebral aneurysm; these patients were operated on at our institution's Neurosurgery and Interventional Radiology Department between 2011 and June 2015. All of the data were obtained retrospectively from medical records.
Results: The hormonal abnormalities observed in the initial 24 h after ictus in subjects with subarachnoid SAH were caused by stressful stimulation aggravated by intracranial bleeding.
Conclusions: The elevated prolactin levels that occur in patients with aSAH can be used in conjunction with other auxiliary factors that we believe may be beneficial to vasospasm.
Bağlantı
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5560194&blobtype=pdfhttp://hdl.handle.net/11727/3454