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dc.contributor.authorBozbas, Serife Savas
dc.contributor.authorBozbas, Huseyin
dc.date.accessioned2019-09-18T12:06:37Z
dc.date.available2019-09-18T12:06:37Z
dc.date.issued2016
dc.identifier.issn1007-9327
dc.identifier.urihttps://www.wjgnet.com/1007-9327/full/v22/i6/2024.htm
dc.identifier.urihttp://hdl.handle.net/11727/3960
dc.description.abstractPulmonary vascular disorders including portopulmonary hypertension (PoPHT) are among the common complications of liver disease and are prognostically significant. Survival is very low without medical treatment and liver transplantation. With advances in medical therapy for elevated pulmonary artery pressure (PAP) and liver transplant surgery, survival of patients with PoPHT and advanced liver disease is significantly improved. Because of the prognostic significance of PoPHT and the limited donor pool, a comprehensive preoperative cardio-pulmonary assessment is of great importance in cirrhotic patients prior to transplant surgery. Therefore, a detailed transthoracic Doppler echocardiographic examination must be an essential component of this evaluation. Patients with mild PoPHT can safely undergo liver transplant surgery. In cases of moderate to severe PoPHT, right heart catheterization (RHC) should be performed. In patients with moderate to severe PoPHT on RHC (mean PAP 35-45 mmHg), vasodilator therapy should be attempted. Liver transplantation should be encouraged in cases that demonstrate a positive response. Bridging therapy with specific pulmonary arterial hypertension treatment agents should be considered until the transplant surgery and should be continued during the peri-and post-operative periods as needed.en_US
dc.language.isoengen_US
dc.relation.isversionof10.3748/wjg.v22.i6.2024en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectportopulmonary hypertensionen_US
dc.subjectpulmonary arterial hypertensionen_US
dc.subjectliver diseaseen_US
dc.subjectliver transplantationen_US
dc.subjectportal hypertensionen_US
dc.titlePortopulmonary hypertension in liver transplant candidatesen_US
dc.typearticleen_US
dc.relation.journalWORLD JOURNAL OF GASTROENTEROLOGYen_US
dc.identifier.volume22en_US
dc.identifier.issue6en_US
dc.identifier.startpage2024en_US
dc.identifier.endpage2029en_US
dc.identifier.wos000368559400008en_US
dc.identifier.scopus2-s2.0-84956707945en_US
dc.contributor.pubmedID26877607en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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