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dc.contributor.authorBalcan, Baran
dc.contributor.authorOlgun, Sehnaz
dc.contributor.authorTorlak, Fatih
dc.contributor.authorSagmen, Seda Beyhan
dc.contributor.authorEryuksel, Emel
dc.contributor.authorKarakurt, Sait
dc.date.accessioned2019-09-22T10:34:21Z
dc.date.available2019-09-22T10:34:21Z
dc.date.issued2015
dc.identifier.issn1302-7808
dc.identifier.urihttp://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5793766&blobtype=pdf
dc.identifier.urihttp://hdl.handle.net/11727/3980
dc.description.abstractOBJECTIVES: Sepsis is a disease with high mortality that is frequently observed in intensive care units. This study aimed to determine the risk factors affecting mortality of patients with sepsis who were followed up in the intensive care unit (ICU). We aimed to contribute to literature by evaluating the relationship between mortality and pro-brain natriuretic peptide (pro-BNP9), C-reactive protein (CRP), thrombocyte count, Acute Physiology and Chronic Health Evaluation (APACHE) II score, Sequential Organ Failure Assessment (SOFA) score, duration of hospitalization in the intensive care unit, and the presence of multidrug-resistant microorganism. MATERIAL AND METHODS: Patients hospitalized in ICU because of the diagnosis of sepsis and septic shock between December 2010 and June 2012 were included in this retrospective study. RESULTS: A total of 141 patients, including 74 male (52.5%) and 67 female (47.5%) patients, were involved in the study, and the median age was 66.8 +/- 17.9 years. Sixty-nine patients (48.9%) were discharged from the ICU; however, 72 patients (51.1%) were exitus. Multi-drug-resistant microorganism was detected in 34 patients (24.1%). The patients' median SOFA score was 9.16 +/- 3.16, median APACHE-II score was 24.9 +/- 7.83, and median duration of hospitalization in the ICU was 8.44 +/- 11.61 days. It was found that mortality rate significantly increased in patients with the APACHE-II score of 24.5 and over, SOFA score of 8.5 and over, pro BNP value of 7241 ng/L and over, and CRP value of 96.5 mg/dL and over. Mortality rate was detected to be higher in patients undergoing invasive mechanical ventilation than in patients undergoing non-invasive mechanical ventilation. When thrombocyte count and mortality were associated with each other, it was found that the median value was 86000 mg/dL in exitus patients, whereas it was 185000 mg/dL in patients discharged from the ICU. CONCLUSION: It was revealed that increased APACHE-II score, increased SOFA score, increased pro BNP score, increased CRP, the presence of multidrug-resistant microorganism, and decreased thrombocyte count elevated the rate of mortality. However, no relationship was observed between the duration of hospitalization in the ICU and mortality.en_US
dc.language.isoengen_US
dc.relation.isversionof10.5152/ttd.2015.4510en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSepsisen_US
dc.subjectmortalityen_US
dc.subjectintensive careen_US
dc.titleDetermination of Factors Affecting Mortality of Patients with Sepsis in a Tertiary Intensive Care Uniten_US
dc.typearticleen_US
dc.relation.journalTURKISH THORACIC JOURNALen_US
dc.identifier.volume16en_US
dc.identifier.issue3en_US
dc.identifier.startpage128en_US
dc.identifier.endpage132en_US
dc.identifier.wos000370845000005


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