The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer
dc.contributor.author | Kuzgunbay, Baris | |
dc.contributor.author | Yaycioglu, Ozgur | |
dc.date.accessioned | 2019-11-26T08:46:30Z | |
dc.date.available | 2019-11-26T08:46:30Z | |
dc.date.issued | 2015 | |
dc.identifier.issn | 2148-9580 | |
dc.identifier.uri | 10.4274/jus.515 | |
dc.identifier.uri | http://hdl.handle.net/11727/4242 | |
dc.description.abstract | High-risk prostate cancer (PCa), which is defined as PSA > 20 ng/mL or Gleason Score (GS) > 7 or >= cT3a, accounts for up to 40% of newly diagnosed cases and carries a significant risk of progression and death. However, the best management approach for patients with high-risk PCa is still under debate. Recently, radical prostatectomy (RP) with extended lymphadenectomy (LND) has become popular for the treatment of high-risk PCa with good prognosis in selected patients in the context of multimodal approach. However, decision should be made after all treatments have been discussed by a multidisciplinary team and the patient should be informed about the likelihood of a multimodal approach. On the other hand, necessity of sufficient surgical expertise for RP to keep the level of morbidity acceptable in high-risk PCa patients should be kept in mind. | en_US |
dc.language.iso | eng | en_US |
dc.relation.isversionof | 10.4274/jus.515 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Prostate cancer | en_US |
dc.subject | high-risk patient | en_US |
dc.subject | radical prostatectomy | en_US |
dc.title | The Role of Radical Prostatectomy in the Treatment of Patients with High-Risk Prostate Cancer | en_US |
dc.type | review | en_US |
dc.relation.journal | JOURNAL OF UROLOGICAL SURGERY | en_US |
dc.identifier.volume | 2 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 120 | en_US |
dc.identifier.endpage | 123 | en_US |
dc.identifier.wos | 000218673200001 | en_US |