Is Presence Time of Dermoid Cysts a Risk Factor for Malignancy Potential in Advanced Age?

Abstract

Background: We have aimed to identify the markers for malignant transformation and also determine the differences between the reproductive age and postmenopausal mature cystic teratoma (MCT) patients.

Methods: Between 2008 and 2015, totally 246 patients informations diagnosed as MCT have been examined retrospectively. Demographic characteristics of the patients, preoperative examinations, final pathology results have been evaluated.

Results: It is included 246 patients with a total of 117 postmenopausal, 129 reproductive age in the study. When demographic characteristics, tumor markers and mass size were compared, only Carcino Embryogenic Antigen (CEA) values were found to be statistically significantly higher in postmenopausal patients. Malignancy was detected in 5 patients (2.03%), all of them were in the postmenopausal period, also CA125 and CA15-3 were determined statistically high in malignant patients.

Conclusions: We think that CA125 can be use as marker for MT in MCT as well as on epithelial ovarian tumors. The duration of mass inside the abdomen without being operated can be a risk factor for malignant transformation. Because of this reason even if it is asymptomatic, after MCI diagnose we think that it will be good to operate the patients without losing time for prevention of malignant transformation. Copyright (C) 2019, Taiwan Society of Geriatric Emergency & Critical Care Medicine.