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dc.contributor.authorSimsek, S.Y.
dc.contributor.authorSerbetcioglu, G.
dc.contributor.authorAlemdaroglu, S.
dc.contributor.authorYetkinel, S.
dc.contributor.authorDurdag, G.D.
dc.contributor.authorCelik, H.
dc.date.accessioned2020-07-28T12:30:17Z
dc.date.available2020-07-28T12:30:17Z
dc.date.issued2019
dc.identifier.issn2468-7847en_US
dc.identifier.urihttp://hdl.handle.net/11727/4798
dc.description.abstractObjective: To determine cilinicopathologic characteristics of recurrent endometrioid type endometrial cancer patients and analyze the methods applied in detection of recurrent disease during follow-up period. Methods: We have retrospectively reviewed the file records of the 226 patients who had endometrioid type carcinoma. Bimanual pelvic examination, speculum examination, carcinogenic antigen-125 (CA125) testing, vaginal cuff cytologic screening, transabdominal ultrasound (TAUS) and transvaginal ultrasound (TVUS) imagings were performed within the context of routine follow-up control examinations in the post-treatment period in every 3 months within the first 2 years and in every 6 months in the following 2 years and with annual control in the consecutive years. Results: Mean follow-up durations was 25.7 +/- 18.9 months while recurrence rate was 3.1%. The study patient group underwent totally 1116 times TVUS and 1084 times whole TA-US evaluations, 973 times vaginal cuff cytological screening, 1125 times pelvic and general physical examinations beside 1060 times CA-125 testings were performed in accordance with our routinely performed follow-up protocol. The asymptomatic recurrent cases; one of those was dignosed with pelvic examination while diagnosis was established using TA-USG evaluation in the other asymptomatic patient. The other 5 cases were symptomatic. Pelvic examination, Computed Tomograhy and Magnetic Resonance Imaging were utilized in diagnosing 1, 3 and 1 of those patients, respectively. Conclusion: The presence of symptoms and pelvic examination seem to be the most effective modalities in detecting recurrence in follow-up of endometrial cancer. It would be reasonable to optimize intervals between follow-up visits and to determine the appropriate evaluations by considering risk levels of the patients. (C) 2019 Elsevier Masson SAS. All rights reserved.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1016/j.jogoh.2019.06.004en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEndometrial canceren_US
dc.subjectCA 125en_US
dc.subjectcervico-vaginal cytologyen_US
dc.subjectultrasonographyen_US
dc.titleClinicopathologic characteristics of recurrent endometrioid endometrial cancer patients and analysis of methods used duriing surveillanceen_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF GYNECOLOGY OBSTETRICS AND HUMAN REPRODUCTIONen_US
dc.identifier.volume48en_US
dc.identifier.issue7en_US
dc.identifier.startpage473en_US
dc.identifier.endpage477en_US
dc.identifier.wos000503810100006en_US
dc.identifier.scopus2-s2.0-85067506848en_US
dc.contributor.pubmedID31212025en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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