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dc.contributor.authorInci, Saadet Demirtas
dc.contributor.authorSade, Leyla Elif
dc.contributor.authorAltin, Cihan
dc.contributor.authorPirat, Bahar
dc.contributor.authorPamukcu, Hilal Erken
dc.contributor.authorYilmaz, Sabriye
dc.contributor.authorMuderrisoglu, Haldun
dc.date.accessioned2020-10-09T07:57:33Z
dc.date.available2020-10-09T07:57:33Z
dc.date.issued2019
dc.identifier.issn1016-5169en_US
dc.identifier.urihttps://archivestsc.com/tr/jvi.aspx?un=TKDA-94728
dc.identifier.urihttp://hdl.handle.net/11727/4835
dc.description.abstractObjective: There are various cardiovascular abnormalities in end-stage liver disease (ESLD). In these patients, left ventricular (LV) systolic function is normal at rest but deteriorates during stress. This deterioration may be due to subclinical myocardial dysfunction. This study evaluated global LV and right ventricular (RV) functions using 2-dimensional (2D) speckle tracking in patients with ESLD. Methods: Forty liver transplant candidates with ESLD and 26 healthy individuals were included in the study. All of the patients underwent conventional echocardiographic measurement. Longitudinal, circumferential, and radial strain measurements, as well as apical and parasternal short-axis image recordings were obtained. All 2D strain measurements were measured with offline analysis using velocity vector imaging (VVI) software. Results: In the apical 4- and 2-chamber measurements, the LV mean longitudinal strain was significantly lower in the patient group compared with that of the control group (-16.0 +/- 3.2% versus -17.6 +/- 2.2%, -16.7 +/- 3.3% versus -18.7 +/- 2.1 +/- 2.1 %; p=0.002, respectively). The LV mean circumferential strain did not differ between groups. The LV mean radial strain and RV longitudinal strain were significantly lower in the patient group (45.4 +/- 10.7 vs. 52.7 +/- 10.8%; p=0.01 and -19.2 +/- 3.5% versus -21.5 +/- 3.6%; p=0.03, respectively). Conclusions: Subclinical impairment of global LV and RV systolic functions was determined in liver transplantation candidates using VVI. This deterioration was detected in longitudinal and radial deformation rather than circumferential deformation mechanics, which is consistent with early-stage LV myocardial dysfunction.en_US
dc.language.isoengen_US
dc.relation.isversionof10.5543/tkda.2019.94728en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEchocardiographyen_US
dc.subjectend-stage liver diseaseen_US
dc.subjectstrainen_US
dc.titleSubclinical myocardial dysfunction in liver transplant candidates determined using speckle-tracking imagingen_US
dc.typearticleen_US
dc.relation.journalTURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGYen_US
dc.identifier.volume47en_US
dc.identifier.issue8en_US
dc.identifier.startpage638en_US
dc.identifier.endpage645en_US
dc.identifier.wos000500929700003en_US
dc.identifier.scopus2-s2.0-85075985622en_US
dc.contributor.pubmedID31802775en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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