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In Vitro Caco-2 Cell Permeability Studies of Ziprasidone Hydrochloride Monohydrate Nanocrystals
(2021)
Objectives: The current study focused on the evaluation of the cytotoxic effect and permeability of ziprasidone hydrochloride monohydrate (ZHM) nanocrystals on Caco-2 cells.
Materials and Methods: ZHM nanocrystals were ...
A Bayesian Estimation Framework for Pharmacogenomics Driven Warfarin Dosing: A Comparative Study
(2015)
The incorporation of pharmacogenomics information into the drug dosing estimation formulations has been shown to increase the accuracy in drug dosing and decrease the frequency of adverse drug effects in many studies in ...
Electrochemical Detection of Antioxidant Activities of 4-Indolyl-5-Oxo-6,6 (Or 7,7)-Dimethyl-1,4,5,6,7,8-Hexahydroquinoline Derivatives
(2021)
Antioxidants used in different medical and industrial fields in order to prevent and delay oxidative stress. They play a crucial role in the protecting biological systems against many diseases. 1,4-dihydropyridines are ...
Preparation and in vitro/in vivo evaluation of flurbiprofen nanosuspension-based gel for dermal application
(2020)
Flurbiprofen (FB) is an analgesic and anti-inflammatory drug, but its low water solubility (BCS Class II) limits its dermal bioavailability. The aim of this study is to develop a FB nanosuspension (NS) based gel and to ...
Sensor-based MIP technologies for targeted metabolomics analysis
(2022)
In recent years, metabolomics, identification and profiling of metabolites, have gained broad interest compared to other omics technologies and are progressively being utilized for biomarker discoveries. Therefore, the ...
Food plant with antioxidant, tyrosinase inhibitory and antimelanoma activity: Prunus mahaleb L
(2022)
Prunus mahaleb L. seeds are used as spice and folk remedies in many countries. The aim of this study was bioactivity guided isolation and characterization phytoconstituents of P. mahaleb which have been studied very limited ...