Snapshot evaluation of acute and chronic heart failure in real-life in Turkey: A follow-up data for mortality
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Tarih
2020Yazar
Yilmaz, Mehmet Birhan
Aksakal, Emrah
Aksu, Ugur
Altay, Hakan
Nesligul, Yildirim
Celik, Ahmet
Akil, Mehmet Ata
Bekar, Lutfu
Vural, Mustafa Gokhan
Guvenc, Rengin Cetin
Ozer, Savas
Ural, Dilek
Cavusoglu, Yuksel
Tokgozoglu, Lale
Üst veri
Tüm öğe kaydını gösterÖzet
Objective: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided.
Methods: This is a prospective outcome analysis of SELFIE-TR. Patients were classified as acute HF (AHF) versus chronic HF (CHF) and HF with reduced ejection fraction (HFrEF), HF with mid-range ejection fraction, and HF with preserved ejection fraction and were followed up for ACM.
Results: There were 1054 patients with a mean age of 63.3 +/- 13.3 years and with a median follow-up period of 16 (7-17) months. Survival data within 1 year were available in 1022 patients. Crude ACM was 19.9% for 1 year in the whole group. ACM within 1 year was 13.7% versus 32.6% in patients with CHF and AHF, respectively (p<0.001). Angiotensin-converting enzyme inhibitor/angiotensin receptor blocker, beta blocker, and mineralocorticoid receptor antagonist were present in 70.6%, 88.2%, and 50.7%, respectively. In the whole cohort, survival curves were graded according to guideline-directed medical therapy (GDMT) scores <= 1 versus 2 versus 3 as 28% versus 20.2% versus 12.2%, respectively (p<0.001). Multivariate analysis of the whole cohort yielded age (p=0.009) and AHF (p=0.028) as independent predictors of mortality in 1 year.
Conclusion: One-year mortality is high in Turkish patients with HF compared with contemporary cohorts with AHF and CHF. Of note, GDMT score is influential on 1-year mortality being the most striking one on chronic HFrEF. On the other hand, in the whole cohort, age and AHF were the only independent predictors of death in 1 year.
Bağlantı
https://jag.journalagent.com/anatoljcardiol/pdfs/AJC_23_3_160_168.pdfhttp://hdl.handle.net/11727/6169
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