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dc.contributor.authorCaglar, Ozgur
dc.contributor.authorOtgun, Ibrahim
dc.contributor.authorComert, Hatice Yalcin
dc.contributor.authorGencoglu, Arzu
dc.contributor.authorBaskin, Esra
dc.date.accessioned2021-08-17T11:57:41Z
dc.date.available2021-08-17T11:57:41Z
dc.date.issued2020
dc.identifier.urihttps://assets.cureus.com/uploads/original_article/pdf/26534/1612429614-1612429608-20210204-18204-1rlfaut.pdf
dc.identifier.urihttp://hdl.handle.net/11727/6276
dc.description.abstractBackground There are few reports about parathyroidectomy due to secondary hyperparathyroidism in patients with end-stage renal failure in the literature. We aimed to evaluate the surgical treatment methods and the results of patients who were operated for secondary hyperparathyroidism with end-stage renal disease in our center. Method Sixteen patients with the diagnosis of secondary hyperparathyroidism were treated surgically in our center. Demographical data, laboratory findings, and imagining methods were all examined. The effect of the Technetium 99m methoxyisobutylisonitrile (Tc-99m-MIBI) probe sensitive to gamma rays detection was also evaluated to locate and identify all the parathyroid glands during the operation. Results Eleven of the patients underwent intravenous (IV) Tc-99m MIBI preoperatively and a gamma probe was detected during surgery. The gamma probe was not used in five patients. Four parathyroid glands were removed in eight (72.7%) out of 11 patients with gamma probes and three parathyroid glands were found in three patients. Total parathyroidectomy and parathyroid autoimplantation were made to eight patients who had removed four glands, subtotal parathyroidectomy was done for the other patients. On a comparison of laboratory findings before and after the surgery, there was a significant relationship between the decrease of serum parathyroid hormone and calcium levels (p<0.05). Conclusion Total parathyroidectomy and parathyroid autoimplantation is the most efficient and safe mode of management for secondary parathyroidism patients. During the surgery, using a probe sensitive to gamma rays detection may also help the surgeon. Thus, unnecessary dissections to prevent the presence of atypical parathyroid glands are prevented.en_US
dc.language.isoengen_US
dc.relation.isversionof10.7759/cureus.6629en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectsecondary hyperparathyroidismen_US
dc.subjectgamma probe detectionen_US
dc.subjecttc-99m-mibien_US
dc.subjectend-stage renal diseaseen_US
dc.titleEffectiveness of the Gamma Probe in Childhood Parathyroidectomy: Retrospective Studyen_US
dc.typearticleen_US
dc.relation.journalCUREUSen_US
dc.identifier.volume12en_US
dc.identifier.issue1en_US
dc.identifier.wos000506832200003en_US
dc.identifier.eissn2168-8184en_US
dc.contributor.pubmedID31966944en_US
dc.contributor.orcID0000-0003-4631-1683en_US
dc.contributor.orcID0000-0003-4361-8508en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDABG-1864-2020en_US
dc.contributor.researcherIDB-5785-2018en_US


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