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dc.contributor.authorUysal, Nihal S.
dc.contributor.authorGulumser, Cagri
dc.contributor.authorYanik, Fiiz F. Bilgin
dc.contributor.authorOnalan, Goegsen
dc.contributor.authorZeyneloglu, Hulusi B.
dc.date.accessioned2021-08-17T12:15:43Z
dc.date.available2021-08-17T12:15:43Z
dc.date.issued2020
dc.identifier.issn1341-8076en_US
dc.identifier.urihttp://hdl.handle.net/11727/6279
dc.description.abstractAim To compare the outcome of intracytoplasmic sperm injection (ICSI) pregnancies complicated by spontaneous loss of a dichorionic co-twin with that of singleton ICSI pregnancies. Methods The study group included dichorionic ICSI pregnancies with co-twin loss (n = 33) and the control group included ICSI pregnancies with a singleton from the beginning (n = 327). Primary outcome measures were obstetric complications, including preterm delivery, newborn small for gestational age, gestational diabetes, gestational hypertensive disorders and abruptio placenta; admission to neonatal intensive care unit (NICU) and perinatal mortality observed in the study and control groups. Statistical analysis was performed using spss for Windows, version 22.0. Results In the study group, there were 26 cases of first trimester (early) and 7 cases of second or third trimester (late) co-twin losses. Mean gestational age at delivery and mean birth weight were significantly lower in the whole study group compared to control (P < 0.05). Preterm delivery and NICU admission rates were significantly higher in the whole study group, compared to control (39.3% vs 14.6% and 36.36% vs 11.69% respectively, P < 0.05), but did not show significant difference between early loss subgroup and control (P > 0.05). Preterm delivery rate was significantly higher in the late loss subgroup compared to the early loss subgroup (85.71% vs 26.92% P < 0.05). Conclusion Loss of a co-twin in dichorionic ICSI pregnancies is associated with increased risk of preterm birth. This risk is significantly higher in cases with late loss compared to the early loss cases.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1111/jog.14177en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfertilization in vitroen_US
dc.subjectfetal deathen_US
dc.subjectintracytoplasmic sperm injectionsen_US
dc.subjectmultiple pregnancyen_US
dc.subjectpregnancy outcomeen_US
dc.titleOutcome of ICSI pregnancies with spontaneous loss of a co-twin compared with singleton ICSI pregnancies: Single center experienceen_US
dc.typearticleen_US
dc.relation.journalJOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCHen_US
dc.identifier.volume46en_US
dc.identifier.issue3en_US
dc.identifier.startpage445en_US
dc.identifier.endpage450en_US
dc.identifier.wos000506567000001en_US
dc.identifier.scopus2-s2.0-85078627575en_US
dc.contributor.pubmedID31922328en_US
dc.contributor.orcID0000-0001-5385-5502en_US
dc.contributor.orcID0000-0002-0289-2642en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDAAA-9475-2020en_US
dc.contributor.researcherIDB-6487-2009en_US


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