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dc.contributor.authorKucukyildiz, Irem Alyazici
dc.contributor.authorGunakan, Emre
dc.contributor.authorAkilli, Huseyin
dc.contributor.authorHaberal, Asuman Nihan
dc.contributor.authorKuscu, Esra
dc.contributor.authorHaberal, Ali
dc.contributor.authorAyhan, Ali
dc.date.accessioned2021-08-20T11:45:37Z
dc.date.available2021-08-20T11:45:37Z
dc.date.issued2020
dc.identifier.issn2363-8397en_US
dc.identifier.urihttp://hdl.handle.net/11727/6297
dc.description.abstractPurpose Endometrioid-type endometrial cancer is usually diagnosed in the early stages and has a good prognosis. Patients with stage 1 disease have survival rates over 95%. Tumor factors affect survival in these patients, but polyp-originated growing has not been sufficiently discussed in the literature. This study aimed to determine the effect of polyp-originated growing in stage 1 endometrioid-type endometrial cancer and to provide a review of the literature. Methods This study includes 318 stage 1 endometrioid-type endometrial cancer patients. The patients were divided into two groups based on the tumor origin. Group I included patients with polyp-originated growing tumors, and Group II included patients with endometrial surface-originated growing tumors. Results Groups I and II included 39 and 279 patients, respectively. The general properties of the patients were similar; there were no significant differences. The univariate survival analyses showed that overall survival for Groups I and II was 65.5 and 83.6 months, respectively; this difference was statistically significant (p = 0.002). The multivariate analysis of age, maximum tumor diameter, tumor origin, lymphovascular space involvement, myometrial invasion depth and tumor grade showed that polyp-originated growing was independently and significantly associated with overall survival (HR 4.05; 95% CI 1.2-13.5; p = 0.023). Conclusion Polyp-originated growing may be a prognostic factor for early stage endometrioid-type endometrial cancer. The prognostic effect of polyp-originated growing is not well known, and further investigation is necessary.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1007/s40944-019-0351-9en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndometrial polypen_US
dc.subjectEndometrioid-type endometrial canceren_US
dc.subjectEndometrial canceren_US
dc.subjectOverall survivalen_US
dc.titleDoes Polyp-Originated Growing have Prognostic Significance for Stage 1 Endometrioid-Type Endometrial Cancer?en_US
dc.typearticleen_US
dc.relation.journalINDIAN JOURNAL OF GYNECOLOGIC ONCOLOGYen_US
dc.identifier.volume18en_US
dc.identifier.issue1en_US
dc.identifier.wos000501019100001en_US
dc.identifier.scopus2-s2.0-85075754591en_US
dc.contributor.orcID0000-0002-5240-8441en_US
dc.contributor.orcID0000-0002-0992-6980en_US
dc.contributor.orcID0000-0001-9852-9911en_US
dc.contributor.orcID0000-0002-1486-7209en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDAAX-3230-2020en_US
dc.contributor.researcherIDAAI-8792-2021en_US
dc.contributor.researcherIDAAK-4587-2021en_US
dc.contributor.researcherIDAAI-9331-2021en_US


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