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dc.contributor.authorRahatli, Feride Kural
dc.contributor.authorSezer, Taner
dc.contributor.authorHas, Arzu Ceylan
dc.contributor.authorAgildere, Ahmet Muhtesem
dc.date.accessioned2021-08-20T11:58:33Z
dc.date.available2021-08-20T11:58:33Z
dc.date.issued2020
dc.identifier.issn1590-1874en_US
dc.identifier.urihttp://hdl.handle.net/11727/6298
dc.description.abstractBackground Frontal lobe epilepsy (FLE) is the most common epilepsy syndrome in the pediatric population; however, brain magnetic resonance imaging (MRI) of the children with FLE is frequently normal. We use both cortical thickness and brain volume measurements to report on cortical changes in children with FLE. Our aim was to determine cortical thickness and brain volume changes on 3 Tesla MRI of children with FLE and normal brain magnetic resonance imaging. Methods Twenty-seven children with FLE and 27 healthy controls received brain magnetic resonance imaging. Cortical thickness and regional brain volumes were assessed using three-dimensional volumetric T1-weighted imaging and patients were compared with controls. Results In children with FLE, statistically significant (p < 0.05) cortical thinning were found in the bilateral middle frontal gyrus, bilateral occipitotemporal and medial lingual gyrus, left subcallosal gyrus, left short insular gyrus, and right long insular gyrus. Statistically significant volume reductions in right and left hemisphere cortical white matter, total cortical white matter, bilateral thalamus, bilateral putamen, bilateral globus pallidus, right caudate nucleus, brain stem, and right cerebellar cortex were found. Conclusion Cortical thinning in frontal and extra-frontal lobes and volume loss in a variety of brain regions were found in children with FLE.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1007/s10072-019-04135-4en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCortical thicknessen_US
dc.subjectBrain volumeen_US
dc.subjectChildrenen_US
dc.subjectFrontal lobe epilepsyen_US
dc.subjectMagnetic resonance imagingen_US
dc.titleEvaluation of cortical thickness and brain volume on 3 Tesla magnetic resonance imaging in children with frontal lobe epilepsyen_US
dc.typearticleen_US
dc.relation.journalNEUROLOGICAL SCIENCESen_US
dc.identifier.volume41en_US
dc.identifier.issue4en_US
dc.identifier.startpage825en_US
dc.identifier.endpage833en_US
dc.identifier.wos000500643300002en_US
dc.identifier.scopus2-s2.0-85076018253en_US
dc.contributor.pubmedID31802343en_US
dc.contributor.orcID0000-0002-2278-1827en_US
dc.contributor.orcID0000-0003-4223-7017en_US
dc.contributor.orcID0000-0002-4226-4034en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDAAJ-5931-2021en_US
dc.contributor.researcherIDAAB-5802-2020en_US
dc.contributor.researcherIDAAL-9808-2021en_US


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