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dc.contributor.authorBagir, Gulay Simsek
dc.contributor.authorHaydardedeoglu, Filiz Eksi
dc.date.accessioned2022-06-24T07:43:05Z
dc.date.available2022-06-24T07:43:05Z
dc.date.issued2021
dc.identifier.issn0947-7349en_US
dc.identifier.urihttp://hdl.handle.net/11727/7144
dc.description.abstractObjectives This study aimed to evaluate the current situation of hypoparathyroid patients and to investigate the relationship between treatment adherence and quality of life. Study design Prospective, multicentre study. Methods Adult patients presenting with the diagnosis of hypoparathyroidism to 20 different endocrinology clinics were included. They were receiving conventional therapies for hypoparathyroidism, using calcium, active vitamin D, and magnesium. We collected data on demographic features, disease- and treatment-related information, and results of routine laboratory tests, treatment adherence, and presence of complications. Beck Depression Inventory, Beck Anxiety Inventory, and Short Form-36 quality of life assessments were administered. Results Among the 300 patients studied, 60.7 % were adherent to their treatment, and 34.1 % had complications. Anxiety and depression scores were significantly higher in non- adherent versus treatment-adherent patients (p < 0.001 and p = 0.001, respectively). Most of the domains of quality-of-life scores were also significantly lower in non-adherent patients. Both anxiety and depression scores showed significant, negative correlations with serum calcium and magnesium concentrations ( r = -0.336, p < 0.001 and r = -0.258, p < 0.001, respectively). Conclusions Nearly 40 % of the patients were non-adherent to conventional treatment for hypoparathyroidism, and such patients had higher anxiety and depression scores and poorer quality of life scores. Conventional treatment might not be sufficient to meet the needs of patients with hypoparathyroidism. In addition to seeking new therapeutic options, factors influencing quality of life should also be investigated and strategies to improve treatment adherence should be developed.en_US
dc.language.isoengen_US
dc.relation.isversionof10.1055/a-1400-2668en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthypoparathyroidismen_US
dc.subjectconventional treatmenten_US
dc.subjecttreatment adherenceen_US
dc.subjectquality of lifeen_US
dc.titleEffects of Treatment Adherence on Quality of Life in Hypoparathyroid Patientsen_US
dc.typearticleen_US
dc.relation.journalEXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETESen_US
dc.contributor.departmentBaşkent Üniversitesien_US
dc.identifier.volume129en_US
dc.identifier.issue12en_US
dc.identifier.startpage918en_US
dc.identifier.endpage925en_US
dc.identifier.wos000726982100009en_US
dc.identifier.scopus2-s2.0-85102589360en_US
dc.contributor.pubmedID33694151en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US


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