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dc.contributor.authorKoseler, Esra
dc.contributor.authorKiziltan, Gul
dc.contributor.authorTurker, Perim Fatma
dc.contributor.authorSaka, Mendane
dc.contributor.authorOk, Mehtap Akcil
dc.contributor.authorBacanli, Didem
dc.contributor.authorAydos, Tolga Resat
dc.contributor.authorBayraktar, Nilufer
dc.contributor.authorOzdemir, Handan
dc.date.accessioned2023-05-11T08:22:45Z
dc.date.available2023-05-11T08:22:45Z
dc.date.issued2018
dc.identifier.issn1129-8723en_US
dc.identifier.urihttp://hdl.handle.net/11727/8983
dc.description.abstractObjective: Dietary fructose from added sugar as high fructose corn syrup may causes major risks in obesity, hyperlipidemia, cardiovascular diseases, hyperuricemia and fatty liver. The aim of this study was to investigate and compare the effects of high fructose and high glucose intake on body weight and some biochemical parameters in rats. Subject and methods: The study was conducted on adult, 32 Wistar albino male rats (300-350 g weeks) which fed with standard laboratory chow. In each group, 8 rats was selected randomly and which was be composed four groups. The rats in each group, in addition to standard meal, different amount of glucose and fructose containing solutions (10% and 30% glucose-fed group, 10% and 30% fructose-fed group) was given by oral gavage for 6 weeks. At baseline and after 6 weeks total cholesterol, VLDL-cholesterol, triglycerides, uric acid, AST and ALT as biochemical parameters and liver histopathological examination of rats were determined. Body weight of the rats was evaluated every week. Results: The 30% fructose group caused higher AST levels according to 10% glucose group, 30% glucose group and 10% fructose group. At the end of 6 weeks, the mean body weight in the fructose-fed groups was higher than the glucose-fed groups (p>0.05). No statistically significant difference between rat groups' portal inflammation rates were found and the moderate and severe ballooning were observed in 30% fructose rats (p<0.05). Conclusions: As a result, dietary fructose from added sugar as high fructose corn syrup may causes major metabolic disorders.en_US
dc.language.isoengen_US
dc.relation.isversionof10.23751/pn.v20i1.5956en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfructoseen_US
dc.subjectglucoseen_US
dc.subjectbody weighten_US
dc.subjectbiochemical parametersen_US
dc.subjectportal inflammationen_US
dc.titleThe Effects of Glucose and Fructose on Body Weight and Some Biochemical Parameters in Ratsen_US
dc.typearticleen_US
dc.relation.journalPROGRESS IN NUTRITIONen_US
dc.identifier.volume20en_US
dc.identifier.issue1en_US
dc.identifier.startpage46en_US
dc.identifier.endpage51en_US
dc.identifier.wos000428874500006en_US
dc.identifier.scopus2-s2.0-85062036233en_US
dc.contributor.orcID0000-0002-4254-3711en_US
dc.contributor.orcID0000-0002-1832-9336en_US
dc.contributor.orcID0000-0002-7886-3688en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDAAZ-8170-2020en_US
dc.contributor.researcherIDAAJ-7279-2020en_US
dc.contributor.researcherIDY-8758-2018en_US


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