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dc.contributor.authorOzgun, Gonca
dc.contributor.authorTepeoglu, Merih
dc.contributor.authorOzdemir, Binnaz Handan
dc.contributor.authorAkcay, Eda Yilmaz
dc.contributor.authorAyva, Ebru Sebnem
dc.contributor.authorDeniz, Emine Ebru
dc.contributor.authorHaberal, Mehmet
dc.date.accessioned2023-06-16T07:46:37Z
dc.date.available2023-06-16T07:46:37Z
dc.date.issued2016
dc.identifier.issn1304-0855en_US
dc.identifier.urihttp://hdl.handle.net/11727/9642
dc.description.abstractObjectives: Our objective was to analyze the incidence of pulmonary disorders in solid-organ transplant recipients and report on outcomes in these patients. Materials and Methods: Seventy liver and kidney transplant patients, who underwent lung biopsy because of pulmonary symptoms between January 2000 and December 2015, were enrolled in the study. We examined and evaluated histopathologic findings of these patients based on clinical data recorded in patients' files. Results: Patients' mean age was 44.5 +/- 16.4 years. Of 70 patients, 25 underwent liver transplant and 45 patients underwent kidney transplant. Forty-six patients received organs from living donors and 24 from deceased donors. Biopsy results of all patients included nonspecific findings (28), organized pneumonia (2), tuberculosis (6), fungal infections (11), tumors (5), amyloidosis (1), diffuse alveolar damage (4), mixed bacterial infection (1), and bronchopneumonia (12). Forty-two patients (60%) died within 54.1 +/- 53.3 months after transplant and 24.6 +/- 41.9 months after lung biopsy. Autopsies were performed on 14 patients. The causes of fatal lung diseases included fungal infections (8), malignant tumors (4), amyloidosis (1), diffuse alveolar damage (4), and mixed bacterial infection (1). Aspergillosis was the most frequently implicated lung infection, occurring in 54.5% of patients with fungal infections. Conclusions: Pulmonary diseases remain an important cause of morbidity and mortality in solid-organ transplant recipients. Fungal infection, especially aspergillosis, was the leading cause of early death in these patients.en_US
dc.language.isoengen_US
dc.relation.isversionof10.6002/ect.tondtdtd2016.P65en_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSolid-organ transplanten_US
dc.subjectLung biopsyen_US
dc.subjectKidneyen_US
dc.subjecttransplanten_US
dc.subjectLiver transplanten_US
dc.subjectFungal infectionen_US
dc.titleLung Biopsy Findings of Patients Who Have Undergone a Liver and Kidney Transplanten_US
dc.typearticleen_US
dc.relation.journalEXPERIMENTAL AND CLINICAL TRANSPLANTATIONen_US
dc.identifier.volume14en_US
dc.identifier.issueSupplement 3en_US
dc.identifier.startpage135en_US
dc.identifier.endpage137en_US
dc.identifier.wos000398457600033en_US
dc.identifier.scopus2-s2.0-85021848161en_US
dc.contributor.pubmedID27805533en_US
dc.contributor.orcID0000-0002-9894-8005en_US
dc.contributor.orcID0000-0002-7528-3557en_US
dc.contributor.orcID0000-0001-6831-9585en_US
dc.contributor.orcID0000-0002-2280-8778en_US
dc.contributor.orcID0000-0002-3462-7632en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.contributor.researcherIDAAK-5222-2021en_US
dc.contributor.researcherIDX-8540-2019en_US
dc.contributor.researcherIDAAK-1960-2021en_US
dc.contributor.researcherIDAAK-1967-2021en_US
dc.contributor.researcherIDAAJ-8097-2021en_US


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